- Microcal Vp-capillary Dsc System User Manual 2017 3 Pdf
- Microcal Vp-capillary Dsc System User Manual Pdf Download Pc
- Microcal Vp-capillary Dsc System User Manual Template
- Microcal Vp-capillary Dsc System User Manual Format
Microcal Vp-capillary Dsc System User Manual 2017 3 Pdf
Product News Oct 10, 2011
Microcal Vp-capillary Dsc System User Manual Pdf Download Pc
GE Healthcare has announced the launch of MicroCal VP-Capillary Differential Scanning Calorimetry (DSC) software for the automated, high throughput analysis of changes in protein stability.
This analytical system enables early characterization of the stability of molecules in solution, providing critical information in protein engineering, from pre-formulation and process development to the formulation of the final biopharmaceutical product.
The new software minimizes the data analysis bottleneck and simplifies experiment design and setup. By providing a single, intuitive graphical user interface for selecting and entering all sample and experiment run parameters, assay development time is kept to a minimum.
The software also streamlines the workflow allowing flexible instrument scheduling, while the automated data sorting and analysis capabilities can reduce the time required for analysis of a typical experiment from days to hours.
The Microcal VP-DSC is a calorimeter that utilizes differential scanning calorimetry (DSC). This method of calorimetry allows the instrument to investigate the stability of numerous biochemical compounds in solution; typical compounds analyzed by this instrument include proteins, nucleic acids, lipids, and detergent micellar systems. For data obtained using the TA Instruments Nano DSC Autosampler system (A, C) and the MicroCal VP-Capillary DSC system (B, D). Sample concentrations were chosen such that the total mass of protein in the calorimeter sample cell was equivalent for proper comparison.
Microcal Vp-capillary Dsc System User Manual Template
Dr Katherine Bowers of Fujifilm Diosynth Biotechnologies commented, “The MicroCal VP-Capillary DSC system has changed the way we design our formulation experiments. For example, the automated sampler requires smaller sample volumes and reduces user variation thereby producing consistent, better quality data. Most of all, the high throughput is supported by the analysis software, which is easy to use and requires no more manual calculations therefore saving us hours. These time savings have really improved our workflow.”
MicroCal VP-Capillary DSC system works by allowing protein unfolding to be studied quickly without the use of labels or artificial probes as it determines the heat absorbed by the sample as the protein unfolds, giving a measure of thermal stability and an indication of long-term stability.
Oct 30, 2015 The MicroCal VP-Capillary DSC is a highly sensitive, fully automated, high-throughput differential scanning calorimeter for characterizing protein. September 11th, 2018 By Verna Frasca. This blog answers FAQs on the new Automated and Manual MicroCal PEAQ-DSC systems. For more information, check your user manual, or contact your regional Malvern Panalytical Support.
The system allows the study of up to 50 samples per day with fully automated cell filling, injection, and cleaning functions thereby enabling unattended operation.
The software is available with all new MicroCal VP-Capillary DSC systems and as an upgrade for current users.
MicroCal Manual Capillary DSC is also available without an auto-sampler for applications where higher throughput and unattended operation and sample handling are not required.